Diseases of sheep and goat

EXAMINATION FOR DISEASE AND PARASITES

Purpose : Identification of animals in the early stages of sickness can aid the farm manager in restricting the spread of disease in the flock and initiating treatment at the earliest.

A. Spotting of sick animals

Sl. no.	Parameter	Healthy animal		Sick animal
Sl. no.	Parameter	Sheep	Goat	Sick animal
1.	Look of animal	Alert		Dull
2.	Head	Raised		Bent downwards
3.	Eyes	Wide open, bright		Dull with white deposition at the corners
4.	Conjunctival m.m.	Normal		Pale or congested
5.	Nose	No discharge		Slimy discharge
6.	Movement	Active		Sluggish, lameness
7.	Response	Quick		Slow
8.	Feces	Normal		Hard / loose, mucus/blood-stained, discolouration, dysentry
9.	Pulse (/min)	70-90	70-90	Increased
10.	Body temperature (^oF)	102.4	103.8	Increased
11.	Respiration (/min)	12-30	12-30	Increased, difficult
12.	Grazing	Normal		Abnormal
13.	Rumination	Regular		Irregular
14.	Feed and water intake	Normal		Reduced
15.	Udder	Normal		May be swollen
16.	Skin	Healthy		Infected, external parasites

B. Sample collection

Samples include blood (microbiology, immunology, hematology, protozoan parasites), feces (endoparasites and enteric pathogens), urine (urinary tract infections), skin scraping (ectoparasites), ruminal fluid (ruminal dysfunction), vaginal discharge (reproductive tract infections)

C. Administration of medicines

Routes include oral (drenching/feeding bolus), parenteral (intra-muscular, intra-venous, intra-peritoneal, sub-cutaneous) and topical.

COMMON DISEASES AND THEIR CONTROL

Morbidity and mortality are the two important factors resulting in heavy losses in sheep production and improvement programmes. Prevention is always better than cure as it is a lot cheaper. This has special significance with sheep as they seem to respond less to treatment when sick than other livestock species. Diseases in sheep can be broadly classified as non-infectious and infectious.

a) Non-infectious diseases

Approximately 80% of deaths in lambs have been estimated due to non-infectious causes. Starvation, primarily from mismothering and behaviour, nutritional and environmental stress, reproductive problems and predation are the major causes reported.

(1) Pneumonia

It is one of the most common and important pathological conditions in sheep. It is characterized clinically by increased respiration, coughing and abdominal breathing. A toll of 20-40% of the mortality has been reported at organized sheep farms due to pneumonia of bacterial or viral origin. Another type of pneumonia is “aspiration” or “drenching” pneumonia caused to wrong and forceful drenching operations. If some fluid has erroneously entered the animal’s respiratory tract, its head should be lowered immediately and slapped a few times.

(2) Ruminal tympany (Bloat)

It is the over-distension of the left flank either due to free gas or froth. This is generally encountered in “greedy feeders” when lush green pasture is available. Tying a bitter (eg. neem) stick in the mouth as a bit to increase secretion of saliva is the most practical and can be done immediately. Oral administration of sweet oil with turpentine oil or at times with formalin is advised.

(3) Rumen acidosis

Ingestion of large amounts of highly fermentable carbohydrate feeds causes an acute illness due to excess production of lactic acid in the rumen. Clinically, the disease is manifested by dehydration, blindness, recumbency, complete rumen stasis and a high mortality rate. Normal saline, sodium bicarbonate and antihistaminics are advised.

(4) Intussusception

It occurs commonly due to nodular worms, change in feed and local intestinal problems. The animal is dull, off-feed, kicking at the belly with no rise of temperature, frequent straining with no defaecation, colic symptoms, and at later stages, recumbency. Emergency surgery is the only rational treatment.

(5) Deficiency diseases

Young sheep grazing on drought-stricken pastures can suffer serious depletion of reserves of minerals and vitamins.

1. Copper and Cobalt : Characterized by anorexia and wasting. Growth and wool production are severely retarded. Wool may be tender or broken. Fine wool becomes limp and glossy and loses crimp, developing straight, steely appearance. Anemia, diarrhoea and unthriftiness occur in extreme cases. Copper or cobalt sulphate treatment causes rapid disappearance of the symptoms.

2. Calcium, Phosphorous & Vit. D : The daily requirement of Ca, P & Vit. D for an adult sheep is about 2.5 gm, 1.5 gm and 300-500 units, respectively. Deficiency may result in rickets in lambs and osteomalacia in adults. Mineral supplementation in diet is essential to prevent this deficiency.

3. Vitamin A : Vit. A deficiency occurs in sheep on dry countryside during periods of drought. Symptoms include night blindness, corneal keratinization, ptyriasis, hoof defects, loss of weight and infertility. Congenital defects are common in the offspring of deficient dams. Animals should have access to green pasture and should be supplied with Vit. A in feed to prevent deficiency.

(6) Pregnancy toxaemia (Ketosis)

It is a highly fatal disease caused due to a decline in the plane of nutrition and short periods of starvation (40 hrs) during the last two months of pregnancy. Hypoglycaemia and hyperketonemia are the primary metabolic disturbances. It is primarily a disease of intensive farming systems. Symptoms include separation from the flock, apparent blindness, constipation, grinding of teeth, drowsiness, tremors of the head, twitching of lips, in-coordination, ketonic breath, leading to coma and death. Treatment comprises intravenous administration of 50% glucose. Supply of molasses in the ration and provision of additional concentrate in the last two months of pregnancy helps prevent the condition.

(7) Poisoning

1. Organochlorine compounds : This group includes DDT, BHC, lindane, aldrin, dieldrin, chlordane, toxaphane, methocychlor etc. which are used as pesticides on crops and as ectoparasiticides on sheep. Toxicity symptoms include increased excitability and irritability followed by muscle tremors, weakness, paralysis etc. Treatment consists of administering antidote, usually short-acting barbiturates.

2. Organophosporous compounds : This group consists of malathion, darathion, chlorathion, carbophenothion, demton, dasnon, dimethylparathion, trichlorphon, dioxalthion etc. Symptoms of toxicity are profuse salivation, muscle stiffness, dyspnoea with open mouth breathing, tremors. Treatment consists of administering antidote, usually atropine sulphate.

3. Snake bite : Sheep are usually bitten on the scrotum or udder. The presence of hair may obscure the typical fang marks. Prolonged pain, muscular weakness, impaired vision, nausea and paralysis are generally exhibited along with symptoms of shock. If anti-venin is not available and the bite is located in an area where a tourniquet cannot be applied, excision of an area of skin and sub-cutaneous tissue can be life-saving.

(8) Wounds

During the monsoon season, a large number of animals suffer from wounds at various sites esp. around the ear, sternum and fore- and hind-legs. The main reason seems to be the awns of Aristidia and Heteropogon species of grasses, which initially break the continuity of the skin, which is then attacked by flies making the wound infected and maggoty. It causes great stress in young lambs, and may also lead to conjunctivitis, corneal opacity and blindness.

(9) Dystokia

The common causes are insufficient opening of the cervical canal, heavy lambs (esp. crossbreds), abnormal fetal position and uterine torsion. The condition can be relieved surgically.

b) Infectious diseases

(1) Blackleg

It is an acute, infectious disease caused by Clostridium chauvoei and characterized by inflammation of muscles, severe toxaemia and high mortality (approaching 100%). All age groups are susceptible. Increased protein feeding of sheep increases their susceptibility. The spores are highly resistant to the environment and the portal of entry is through the alimentary mucosa. Infection in sheep generally takes place through skin wounds following shearing and docking. Symptoms include high fever, anorexia, discolouration of skin, crepitation and depression. Penicillin is the drug o choice for treatment.

(2) Enterotoxaemia (pulpy kidney)

It is an acute disease of sheep of all ages, but primarily of lambs. It affects animals in a high state of nutrition on a lush feed, grass or grain. Morbidity rates seldom exceed 10% but mortality rate approximates 100%. It is caused by Clostridium perfringens type D which normally inhabits the alimentary tract of sheep. Under certain conditions, the organism proliferated rapidly in the intestines and produces lethal quantity of toxin. In lambs, the course of illness is very short, often less than 2 hours and never more than 12 hours, and many are found dead without manifesting early signs. Symptoms include green, pasty diarrhea, staggering, recumbency, opisthotonus, and acute, clonic convulsions with frothing at the mouth. A history of sudden death of several big lambs justifies a tentative diagnosis of enterotoxaemia. Suphadimidine may be effective for treatment. Two major control measures include reduction in the feed intake and vaccination.

Infection with Cl. Perfringens type B (lamb dysentery) and type C (struck, hemorrhagic enterotoxaemia) result in severe enteritis with diarrhea and dysentery in lambs.

(3) Tetanus

It is an acute, infectious disease manifested by tonic convulsions of the voluntary muscles. In sheep, it commonly follows routine operations such as shearing, docking, castration and even vaccination. Clostridium tetani form spores which are capable of persisting in soil for a number of years. The portal of entry is usually through deep, puncture wounds. Symptoms include stiffness of limbs, lock jaw, opisthotonus, followed by death due to asphyxiation. Tetanus antitoxin is usually administered but is of little value when the signs have appeared.

(4) Pasteurellosis

It is primarily caused by Pasteurella haemolytica in sheep and usually occurs in pneumonic form, although a septicaemic form is not uncommon in lambs. Morbidity and mortality rates may be as high as 40%. Transmission occurs by the inhalation or ingestion of the infected material. Symptoms include pyrexia, mucopurulent discharge from the eyes and nose, coughing, depression and anorexia. Preventive vaccination is recommended, after which the animals should not be sent out for grazing for 2-3 days.

(5) Paratuberculosis (Johne’s disease)

It is a chronic, wasting disease caused by Mycobacteirum paratuberculosis and characterized by progressive emaciation and a thickening and corrugation of the intestinal wall. Mortality rate may be as high as 10%. The disease causes severe economic losses in infected flocks. As the progress of the disease is slow, it is mostly seen in older animals. No treatment is successful.

(6) Sheep pox

It is a highly contagious viral disease characterized by development of vesicles and pustules on the skin and internal lesions. Spread may be by contact with infected animals and contaminated articles, or by inhalation. It often causes death in 50% of affected animals. Infection of the pustules by secondary organisms may cause pyrexia and other complications. The course of the disease is 3-4 weeks, during which time the sheep becomes emaciated and may shed their wool. Vaccination is the best control.

(7) Foot and mouth disease

It is an extremely contagious, acute viral disease characterized by development of vesicles in the oral cavity and in the interdigital space. Mortality is usually low (3%), but the economic loss is chiefly due to the loss in condition of the affected animal. Transmission is by contact with the diseased animal and incubation period is less than 24 hrs. Antibiotics are recommended to check secondary infections. Vaccination is the best control.

(8) Contagious ecthyma

It is a viral disease characterized by the formation of papules and pustules and the piling up of thick crusts on the lesions. The virus gains entry through unobserved wounds on the lips. The incubation period is dependant on the amount of virus introduced. The lesions are mostly found on the commissures of the lips and are covered by scabs. The course of the disease is 1-4 weeks. Antibiotics are recommended to check secondary infections.

(9) Blue tongue

It is an infectious but non-contagious, exotic disease of sheep. Natural transmission takes place through insect vectors viz. Culicoides and Aedes species, and sheepked Melophagus ovinus. Incubation period is less than a week. Pyrexia upto 106^oF is the common initial symptom.. The disease has three clinical forms : abortive, acute and sub-acute. The abortive form mostly goes unnoticed. In the acute form, there is fever lasting for 5-6 days with nasal discharge, frothing, marked salivation, highly congested and cyanotic nasal and oral mucosa, epithelial excoriation in the oral cavity and purplish discolouration of the interdigital space, pasterns and coronets. Symptoms are less severe in the sub-acute from. Morbidity rate may be 50% or more whereas mortality rates very widely. Antibiotics are recommended to check secondary infections.

VACCINATION OF SHEEP AND GOATS

Purpose : Prevention of disease plays a major role in increasing profitability in a sheep or goat farm. Vaccination against infectious diseases is an important component of health management.

Vaccination schedule for sheep:-

Disease	Age and booster doses	Route	Remarks
Foot and mouth disease	6-8 weeks; repeat every 6-9 months	s/c or i/m depending on the vaccine
Hemorrhagic Septicaemia	3-4 months; repeat annually	1 ml s/c	May/ June
Sheep pox	3 months	s/c
Tetanus	Tetanus toxoid	0.5 - 1 ml s/c or i/m
Anthrax	4-6 months; repeat annually	0.5 ml s/c at tail fold	In endemic areas only
Enterotoxaemia	3-4 months, repeat after 15 days and then annually.	2.5 ml s/c	First two doses before august

Vaccination schedule for goats:-

Disease	Age and booster doses	Route	Remarks
Foot and mouth disease	6-8 weeks, repeat every 6-9 months	s/c or i/m depending on the vaccine
Enterotoxaemia	3-4 months, repeat after 15 days and then annually.	2.5 ml s/c	First two doses before august
Hemorrhagic Septicaemia	3-4 months,, repeat annually	1ml s/c	May/June
Anthrax	4-6 months, repeat annually	0.5 ml s/c at tail fold	In endemic areas only
Tetanus	3-4 months, repeat at 6 months and then annually	0.5 - 1 ml s/c or i/m